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The researchers looked at 1,005 people who had been diagnosed with these cancers. The blood test found signs of cancer in about 70 percent of them.

They also looked at 812 people without cancer diagnoses and found just seven of them less than 1 percent apparently had a false reading that found cancer. A low false positive rate is critical for any test that could be used widely to screen people for cancer.

Of course, the ultimate goal of this test is to find cancer in people who haven’t already been diagnosed. And that percentage could well be lower than the 70 percent average. For example, the canada goose outlet store quebec test was successful only about 40 percent of the time in the patients the researchers studied with the earliest stage 1 cancers.

Though 40 percent success would be far from ideal, “we still think this is a very important milestone in detecting cancers in asymptomatic people,” Papadopoulos says. “That could save their life.”

“I am incredibly excited by this new paper,” says Joshua Schiffman, an oncologist and cancer researcher at the Huntsman Cancer Center at the University of Utah who was not involved in the study. “This is the paper that’s canada goose outlet toronto address going to set the field in motion.”

But Schiffman points out that there are many issues to work out even assuming the test proves reliable among people who have not been previously diagnosed with cancer. For instance, if the success rate is around 40 percent at detecting cancer, that means it misses cancers more often than it finds it.

“The thing we worry about quite often is. if we have a test result that is negative we don’t want to give false reassurance to the canada goose outlet uk sale patient,” he says. He is concerned that patients will think to themselves, “Even though I have this weird stomach pain that won’t go away, I know it’s not cancer. I’m not going to go to the doctor because the CancerSEEK test told me it was negative,” Schiffman says. “And that would be a terrible thing.”

Canada Goose Parka Another problem is that the test results find signs of cancer, but often fail to pinpoint which part of the body is affected. “That’s a tremendous problem that has to be overcome,” he says. Canada Goose Parka

“We’ve come about one step in a thousand mile journey,” says Vinay Prasad, an oncologist and cancer researcher at the Oregon Health and Science University who was not involved in the study.

First, he notes, the Hopkins team will need to demonstrate that the test will be useful in patients without symptoms. Then the researchers will need to show that the canada goose outlet in chicago rate of false alarms remains very low, otherwise people will be sent on needless and expensive medical odysseys.

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That’s been a huge problem with previous cancer screening tests, especially for prostate cancer and breast cancer, and has led to pointless and potentially dangerous treatments, he says.

An effective screening test would hold lots of potential for cancer patients, Prasad says.

“We want this to be true, we hope that this is true, but we have learned through 30, 40, 50 years of cancer screening that we have to do the right studies at the outset to know that it’s true,” Prasad says.

The scientists at Hopkins have already launched their next study, which could involve tens of thousands of apparently healthy volunteers who are enrolled in the Geisinger Health Plan in Pennsylvania. Their experience will help answer the next big question, which is whether CancerSEEK will pick up cancer in people who don’t have symptoms.

canada goose factory sale If that multiyear experiment succeeds, the researchers will still have to demonstrate that the test improves and extends the lives of cancer patients. canada goose factory sale

Papadopoulos is less concerned that the test could detect cancers that might not in fact benefit from treatment.

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As for the cost of the test, Papadopoulos says the research team has tried hard to make it affordable. They’re hoping to make it economical, so that each test could cost about $500. But canada goose outlet houston he says Johns Hopkins holds the patent and has not licensed it as yet canada goose factory outlet to a company that would ultimately set the price.

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